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oxaliplatin100

 

OXALIPLATIN Medac

Serbuk untuk diberikan secara infus

Komposisi

Oxaliplatin : 100 mg

 

Kegunaan

Terapi adjuvan stadium III (Duke C) kanker usus setelah reseksi lengkap tumor primer dalam kombinasi dengan 5-fluorouracil (5-FU) & folinic acid (FA).

Terapi kanker kolorektal metastatis.

 

Dosis dan Administrasi

Hanya untuk Dewasa. Dosis Adjuvan : 85 mg / m² IV diulang setiap 2 minggu selama 12 siklus (6 bulan). Kanker kolorektal metastatis : 85 mg / m² setiap 2 minggu. Diberikan secara infus dengan larutan infus 250-500 ml Glukosa 5% selama 2-6 jam.

 

Kontraindikasi

Riwayat hipersensitivitas, menyusui, myelosupresi dengan neutrofil dasar

 

Peringatan & Perhatian

Gangguan fungsi ginjal ringan. Riwayat reaksi alergi terhadap bahan platinum. Monitor kondisi syaraf selama terapi dan sesudah terapi secara periodik. Hamil dan masa menyusui.

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Efek Samping

Gastrointestinal : diare, mual, muntah, mukositis, konstipasi, nyeri abdomen, anoreksia. Hematologi : anemia, neutropenia, trombositopenia, leukopenia. Neurologi : neuropati, sakit kepala, gangguan sensoris, rasa lelah, nyeri tulang belakang. Kulit : alopesia, perubahan warna kulit.

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Nomor Registrasi

DKI1030600180A1